STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iscSCysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (389 aa)    
Predicted Functional Partners:
EEG78998.1
TIGRFAM: FeS cluster assembly scaffold protein NifU; PFAM: nitrogen-fixing NifU domain protein; KEGG: mta:Moth_1651 nitrogen-fixing NifU-like.
 
 0.998
EEG78996.1
TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: mta:Moth_1653 transcriptional regulator, BadM/Rrf2 family.
 
 
 0.958
EEG77681.1
TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: mta:Moth_1653 transcriptional regulator, BadM/Rrf2 family.
 
 
 0.957
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
   
 0.894
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 0.840
EEG78532.1
PFAM: SirA family protein; KEGG: mta:Moth_0124 SirA-like; Belongs to the sulfur carrier protein TusA family.
   
 0.831
EEG77652.1
PFAM: SirA family protein; KEGG: mta:Moth_1968 SirA-like; Belongs to the sulfur carrier protein TusA family.
   
 0.793
EEG77657.1
PFAM: SirA family protein; KEGG: mta:Moth_1968 SirA-like; Belongs to the sulfur carrier protein TusA family.
   
 0.793
EEG78778.1
PFAM: beta-lactamase domain protein; Rhodanese domain protein; KEGG: mtp:Mthe_0688 beta-lactamase domain protein.
   
 0.761
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 
 0.754
Your Current Organism:
Dethiobacter alkaliphilus
NCBI taxonomy Id: 555088
Other names: D. alkaliphilus AHT 1, Dethiobacter alkaliphilus AHT 1, Dethiobacter alkaliphilus DSM 19026, Dethiobacter alkaliphilus str. AHT 1, Dethiobacter alkaliphilus strain AHT 1
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