Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EEG77540.1TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: dsy:DSY4887 hypothetical protein. (87 aa)    
Predicted Functional Partners:
EEG78333.1
TIGRFAM: stage III sporulation protein AE; PFAM: Sporulation stage III protein AE; KEGG: drm:Dred_1060 hypothetical protein.
  
    0.959
EEG77108.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
  
 0.885
EEG76624.1
TIGRFAM: transcriptional regulator, AbrB family; stage V sporulation protein T; PFAM: SpoVT/AbrB domain protein; KEGG: drm:Dred_0113 transcriptional regulator, AbrB family.
  
  
 0.877
EEG77579.1
TIGRFAM: stage II sporulation protein R; KEGG: swo:Swol_0063 pro-sigma-E processing factor spoIIR.
  
   
 0.866
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.857
EEG78337.1
TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase; KEGG: pth:PTH_1166 hypothetical protein.
  
   
 0.854
EEG78335.1
TIGRFAM: stage III sporulation protein AC; PFAM: Stage III sporulation AC family protein; KEGG: swo:Swol_0552 hypothetical protein.
  
  
 0.848
EEG78308.1
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.847
EEG78331.1
TIGRFAM: stage III sporulation protein AG; KEGG: tte:TTE1289 stage III sporulation protein AG.
  
  
 0.839
EEG78334.1
TIGRFAM: stage III sporulation protein AD; PFAM: Sporulation stage III protein AD; KEGG: pth:PTH_1169 hypothetical membrane protein.
  
  
 0.831
Your Current Organism:
Dethiobacter alkaliphilus
NCBI taxonomy Id: 555088
Other names: D. alkaliphilus AHT 1, Dethiobacter alkaliphilus AHT 1, Dethiobacter alkaliphilus DSM 19026, Dethiobacter alkaliphilus str. AHT 1, Dethiobacter alkaliphilus strain AHT 1
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