STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEG76582.1PFAM: protein of unknown function DUF523; KEGG: swo:Swol_1164 hypothetical protein. (165 aa)    
Predicted Functional Partners:
EEG76581.1
PFAM: protein of unknown function DUF1312; KEGG: dsy:DSY0901 hypothetical protein.
       0.773
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.773
pth
Aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
      0.709
ddl
D-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
    0.675
EEG79064.1
KEGG: amt:Amet_2163 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK.
 
      0.651
EEG76585.1
PFAM: Orn/Lys/Arg decarboxylase major region; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; Orn/Lys/Arg decarboxylase domain protein; KEGG: pth:PTH_0061 arginine/lysine/ornithine decarboxylases.
  
    0.550
EEG76584.1
CsfB protein; KEGG: bwe:BcerKBAB4_0023 CsfB protein.
       0.536
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
       0.536
EEG78730.1
KEGG: cth:Cthe_0897 deoxyguanosinetriphosphate triphosphohydrolase-like protein; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; Belongs to the dGTPase family. Type 2 subfamily.
    
  0.511
EEG76578.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: chy:CHY_0044 putative keto/oxoacid ferredoxin oxidoreductase, beta subunit.
       0.473
Your Current Organism:
Dethiobacter alkaliphilus
NCBI taxonomy Id: 555088
Other names: D. alkaliphilus AHT 1, Dethiobacter alkaliphilus AHT 1, Dethiobacter alkaliphilus DSM 19026, Dethiobacter alkaliphilus str. AHT 1, Dethiobacter alkaliphilus strain AHT 1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.