node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR999_PMT00770 | DR999_PMT02462 | A0A4D9EXS1 | A0A4D9EU78 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | Solute carrier family 2, facilitated glucose transporter member 5. | 0.484 |
DR999_PMT00770 | DR999_PMT04815 | A0A4D9EXS1 | A0A4D9EUB5 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | Pyruvate dehydrogenase protein X component, mitochondrial. | 0.832 |
DR999_PMT00770 | DR999_PMT05201 | A0A4D9EXS1 | A0A4D9ETR9 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | NEDD8-activating enzyme E1 catalytic subunit. | 0.875 |
DR999_PMT00770 | DR999_PMT12673 | A0A4D9EXS1 | A0A4D9EBK5 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | Putative helicase with zinc finger domain; Belongs to the ubiquitin-conjugating enzyme family. | 0.798 |
DR999_PMT00770 | DR999_PMT18637 | A0A4D9EXS1 | A0A4D9DS86 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | L-amino-acid oxidase-like; Belongs to the ubiquitin-conjugating enzyme family. | 0.800 |
DR999_PMT00770 | DR999_PMT19452 | A0A4D9EXS1 | A0A4D9DMH1 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | E3 ubiquitin-protein ligase TRIM41. | 0.510 |
DR999_PMT02462 | DR999_PMT00770 | A0A4D9EU78 | A0A4D9EXS1 | Solute carrier family 2, facilitated glucose transporter member 5. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | 0.484 |
DR999_PMT02462 | DR999_PMT04275 | A0A4D9EU78 | A0A4D9ENG7 | Solute carrier family 2, facilitated glucose transporter member 5. | ERC protein 2-like isoform 4. | 0.575 |
DR999_PMT02462 | DR999_PMT05201 | A0A4D9EU78 | A0A4D9ETR9 | Solute carrier family 2, facilitated glucose transporter member 5. | NEDD8-activating enzyme E1 catalytic subunit. | 0.648 |
DR999_PMT02462 | DR999_PMT19452 | A0A4D9EU78 | A0A4D9DMH1 | Solute carrier family 2, facilitated glucose transporter member 5. | E3 ubiquitin-protein ligase TRIM41. | 0.548 |
DR999_PMT04275 | DR999_PMT02462 | A0A4D9ENG7 | A0A4D9EU78 | ERC protein 2-like isoform 4. | Solute carrier family 2, facilitated glucose transporter member 5. | 0.575 |
DR999_PMT04275 | DR999_PMT12673 | A0A4D9ENG7 | A0A4D9EBK5 | ERC protein 2-like isoform 4. | Putative helicase with zinc finger domain; Belongs to the ubiquitin-conjugating enzyme family. | 0.747 |
DR999_PMT04275 | DR999_PMT19452 | A0A4D9ENG7 | A0A4D9DMH1 | ERC protein 2-like isoform 4. | E3 ubiquitin-protein ligase TRIM41. | 0.540 |
DR999_PMT04815 | DR999_PMT00770 | A0A4D9EUB5 | A0A4D9EXS1 | Pyruvate dehydrogenase protein X component, mitochondrial. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | 0.832 |
DR999_PMT04815 | DR999_PMT05201 | A0A4D9EUB5 | A0A4D9ETR9 | Pyruvate dehydrogenase protein X component, mitochondrial. | NEDD8-activating enzyme E1 catalytic subunit. | 0.869 |
DR999_PMT04815 | DR999_PMT12673 | A0A4D9EUB5 | A0A4D9EBK5 | Pyruvate dehydrogenase protein X component, mitochondrial. | Putative helicase with zinc finger domain; Belongs to the ubiquitin-conjugating enzyme family. | 0.798 |
DR999_PMT04815 | DR999_PMT18637 | A0A4D9EUB5 | A0A4D9DS86 | Pyruvate dehydrogenase protein X component, mitochondrial. | L-amino-acid oxidase-like; Belongs to the ubiquitin-conjugating enzyme family. | 0.818 |
DR999_PMT04815 | DR999_PMT19452 | A0A4D9EUB5 | A0A4D9DMH1 | Pyruvate dehydrogenase protein X component, mitochondrial. | E3 ubiquitin-protein ligase TRIM41. | 0.510 |
DR999_PMT05201 | DR999_PMT00770 | A0A4D9ETR9 | A0A4D9EXS1 | NEDD8-activating enzyme E1 catalytic subunit. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] | 0.875 |
DR999_PMT05201 | DR999_PMT02462 | A0A4D9ETR9 | A0A4D9EU78 | NEDD8-activating enzyme E1 catalytic subunit. | Solute carrier family 2, facilitated glucose transporter member 5. | 0.648 |