node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDI51519.1 | SDI75299.1 | SAMN04487993_10065 | SAMN04487993_1009160 | Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.982 |
SDI51519.1 | SDI89449.1 | SAMN04487993_10065 | SAMN04487993_101221 | Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Citrate synthase. | 0.973 |
SDI51519.1 | SDJ07581.1 | SAMN04487993_10065 | SAMN04487993_101730 | Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Phosphoenolpyruvate phosphomutase. | 0.851 |
SDI51519.1 | SDJ32951.1 | SAMN04487993_10065 | SAMN04487993_102644 | Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.610 |
SDI51519.1 | glcB | SAMN04487993_10065 | SAMN04487993_102259 | Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.934 |
SDI51519.1 | sucC | SAMN04487993_10065 | SAMN04487993_1006111 | Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.964 |
SDI51519.1 | sucD | SAMN04487993_10065 | SAMN04487993_1006113 | Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.950 |
SDI75299.1 | SDI51519.1 | SAMN04487993_1009160 | SAMN04487993_10065 | Citrate synthase; Belongs to the citrate synthase family. | Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.982 |
SDI75299.1 | SDJ07581.1 | SAMN04487993_1009160 | SAMN04487993_101730 | Citrate synthase; Belongs to the citrate synthase family. | Phosphoenolpyruvate phosphomutase. | 0.890 |
SDI75299.1 | SDJ07599.1 | SAMN04487993_1009160 | SAMN04487993_101731 | Citrate synthase; Belongs to the citrate synthase family. | Hypothetical protein. | 0.543 |
SDI75299.1 | SDJ13588.1 | SAMN04487993_1009160 | SAMN04487993_101946 | Citrate synthase; Belongs to the citrate synthase family. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.516 |
SDI75299.1 | SDJ32951.1 | SAMN04487993_1009160 | SAMN04487993_102644 | Citrate synthase; Belongs to the citrate synthase family. | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.960 |
SDI75299.1 | glcB | SAMN04487993_1009160 | SAMN04487993_102259 | Citrate synthase; Belongs to the citrate synthase family. | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.943 |
SDI75299.1 | leuA | SAMN04487993_1009160 | SAMN04487993_1010108 | Citrate synthase; Belongs to the citrate synthase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.492 |
SDI75299.1 | sucC | SAMN04487993_1009160 | SAMN04487993_1006111 | Citrate synthase; Belongs to the citrate synthase family. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.986 |
SDI75299.1 | sucD | SAMN04487993_1009160 | SAMN04487993_1006113 | Citrate synthase; Belongs to the citrate synthase family. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.854 |
SDI89449.1 | SDI51519.1 | SAMN04487993_101221 | SAMN04487993_10065 | Citrate synthase. | Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.973 |
SDI89449.1 | SDJ07581.1 | SAMN04487993_101221 | SAMN04487993_101730 | Citrate synthase. | Phosphoenolpyruvate phosphomutase. | 0.859 |
SDI89449.1 | SDJ07599.1 | SAMN04487993_101221 | SAMN04487993_101731 | Citrate synthase. | Hypothetical protein. | 0.543 |
SDI89449.1 | SDJ13588.1 | SAMN04487993_101221 | SAMN04487993_101946 | Citrate synthase. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.416 |