STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACX95343.1KEGG: ppw:PputW619_1383 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein. (478 aa)    
Predicted Functional Partners:
ACX95351.1
KEGG: tgr:Tgr7_2083 undecaprenyl-phosphate galactose phosphotransferase; TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase.
  
  
 0.999
ACX95344.1
Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: ppu:PP_1777 phosphomannomutase.
 
 0.998
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
 
 
 0.981
ACX95283.1
PFAM: ROK family protein; KEGG: pla:Plav_2811 ROK family protein.
    
 0.957
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: tgr:Tgr7_0871 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.954
fbp
PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: tgr:Tgr7_0281 inositol phosphatase/fructose-1,6-bisphosphatase.
   
 0.941
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.929
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
    
 0.922
ACX95594.1
PFAM: PTS system fructose subfamily IIA component; KEGG: tgr:Tgr7_0721 PTS system fructose subfamily IIA component.
    
 0.917
ACX95342.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: vap:Vapar_0764 ABC transporter related.
  
  
 0.894
Your Current Organism:
Halothiobacillus neapolitanus
NCBI taxonomy Id: 555778
Other names: H. neapolitanus c2, Halothiobacillus neapolitanus ATCC 23641, Halothiobacillus neapolitanus c2, Halothiobacillus neapolitanus str. c2, Halothiobacillus neapolitanus strain c2
Server load: low (26%) [HD]