node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACX95380.1 | ACX96170.1 | Hneap_0526 | Hneap_1336 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: tgr:Tgr7_2801 anthranilate synthase component II. | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: abo:ABO_1749 P-protein, chorismate mutase/prephenate dehydratase. | 0.660 |
ACX95380.1 | ACX96743.1 | Hneap_0526 | Hneap_1921 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: tgr:Tgr7_2801 anthranilate synthase component II. | Anthranilate synthase; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; KEGG: tgr:Tgr7_1832 anthranilate synthase. | 0.999 |
ACX95380.1 | ACX97051.1 | Hneap_0526 | Hneap_2236 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: tgr:Tgr7_2801 anthranilate synthase component II. | KEGG: app:CAP2UW1_0339 endoribonuclease L-PSP. | 0.900 |
ACX95380.1 | aroB | Hneap_0526 | Hneap_2279 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: tgr:Tgr7_2801 anthranilate synthase component II. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.536 |
ACX95380.1 | aroC | Hneap_0526 | Hneap_1833 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: tgr:Tgr7_2801 anthranilate synthase component II. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.946 |
ACX95380.1 | aroE | Hneap_0526 | Hneap_0694 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: tgr:Tgr7_2801 anthranilate synthase component II. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.644 |
ACX95380.1 | aroK | Hneap_0526 | Hneap_1942 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: tgr:Tgr7_2801 anthranilate synthase component II. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.424 |
ACX95380.1 | trpE | Hneap_0526 | Hneap_2109 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: tgr:Tgr7_2801 anthranilate synthase component II. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
ACX96168.1 | ACX96170.1 | Hneap_1334 | Hneap_1336 | PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: noc:Noc_0176 prephenate dehydrogenase. | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: abo:ABO_1749 P-protein, chorismate mutase/prephenate dehydratase. | 0.954 |
ACX96168.1 | aroA | Hneap_1334 | Hneap_1333 | PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: noc:Noc_0176 prephenate dehydrogenase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.996 |
ACX96168.1 | aroB | Hneap_1334 | Hneap_2279 | PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: noc:Noc_0176 prephenate dehydrogenase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.763 |
ACX96168.1 | aroC | Hneap_1334 | Hneap_1833 | PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: noc:Noc_0176 prephenate dehydrogenase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.880 |
ACX96168.1 | aroE | Hneap_1334 | Hneap_0694 | PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: noc:Noc_0176 prephenate dehydrogenase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.500 |
ACX96168.1 | aroK | Hneap_1334 | Hneap_1942 | PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: noc:Noc_0176 prephenate dehydrogenase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.548 |
ACX96170.1 | ACX95380.1 | Hneap_1336 | Hneap_0526 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: abo:ABO_1749 P-protein, chorismate mutase/prephenate dehydratase. | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: tgr:Tgr7_2801 anthranilate synthase component II. | 0.660 |
ACX96170.1 | ACX96168.1 | Hneap_1336 | Hneap_1334 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: abo:ABO_1749 P-protein, chorismate mutase/prephenate dehydratase. | PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: noc:Noc_0176 prephenate dehydrogenase. | 0.954 |
ACX96170.1 | ACX96743.1 | Hneap_1336 | Hneap_1921 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: abo:ABO_1749 P-protein, chorismate mutase/prephenate dehydratase. | Anthranilate synthase; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; KEGG: tgr:Tgr7_1832 anthranilate synthase. | 0.575 |
ACX96170.1 | aroA | Hneap_1336 | Hneap_1333 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: abo:ABO_1749 P-protein, chorismate mutase/prephenate dehydratase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.983 |
ACX96170.1 | aroB | Hneap_1336 | Hneap_2279 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: abo:ABO_1749 P-protein, chorismate mutase/prephenate dehydratase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.712 |
ACX96170.1 | aroC | Hneap_1336 | Hneap_1833 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: abo:ABO_1749 P-protein, chorismate mutase/prephenate dehydratase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.868 |