STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACX96684.1PFAM: CoA-binding domain protein; GCN5-related N-acetyltransferase; KEGG: tgr:Tgr7_3063 acetyltransferase. (900 aa)    
Predicted Functional Partners:
ACX95796.1
PFAM: KR domain protein; Beta-ketoacyl synthase; Alcohol dehydrogenase GroES domain protein; short-chain dehydrogenase/reductase SDR; Acyl transferase; Alcohol dehydrogenase zinc-binding domain protein; phosphopantetheine-binding; NAD-dependent epimerase/dehydratase; KEGG: npu:Npun_F3360 beta-ketoacyl synthase.
  
  
 0.884
ACX96340.1
PFAM: KR domain protein; Acyl transferase; Beta-ketoacyl synthase; Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KEGG: neu:NE1389 putative type I polyketide synthase WcbR.
  
  
 0.884
ACX96685.1
PFAM: histone deacetylase superfamily; KEGG: bpt:Bpet1899 histone deacetylase family protein.
 
     0.780
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
  
    0.636
ACX96683.1
KEGG: tgr:Tgr7_0688 hypothetical protein.
       0.584
ACX96884.1
KEGG: tmz:Tmz1t_1845 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
  
 
 0.548
argD
KEGG: tgr:Tgr7_2464 acetylornithine and succinylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
   
 
 0.526
ACX94931.1
PFAM: AMP-dependent synthetase and ligase; Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: bcj:BCAL0843 AMP-binding enzyme family protein.
     
 0.515
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
     
 0.512
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
 
    0.461
Your Current Organism:
Halothiobacillus neapolitanus
NCBI taxonomy Id: 555778
Other names: H. neapolitanus c2, Halothiobacillus neapolitanus ATCC 23641, Halothiobacillus neapolitanus c2, Halothiobacillus neapolitanus str. c2, Halothiobacillus neapolitanus strain c2
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.