node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACX95023.1 | murJ | Hneap_0159 | Hneap_2245 | FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: azo:azo0899 hypothetical protein. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.752 |
ACX95063.1 | ileS | Hneap_0200 | Hneap_2232 | TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: FAD synthetase; Riboflavin kinase; KEGG: hip:CGSHiEE_07145 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.784 |
ACX95063.1 | murA | Hneap_0200 | Hneap_0765 | TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: FAD synthetase; Riboflavin kinase; KEGG: hip:CGSHiEE_07145 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.436 |
ACX95063.1 | murJ | Hneap_0200 | Hneap_2245 | TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: FAD synthetase; Riboflavin kinase; KEGG: hip:CGSHiEE_07145 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.838 |
ACX95351.1 | ACX97059.1 | Hneap_0496 | Hneap_2244 | KEGG: tgr:Tgr7_2083 undecaprenyl-phosphate galactose phosphotransferase; TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase. | PFAM: NAD-dependent epimerase/dehydratase; KEGG: noc:Noc_2776 NAD-dependent epimerase/dehydratase. | 0.630 |
ACX95351.1 | murJ | Hneap_0496 | Hneap_2245 | KEGG: tgr:Tgr7_2083 undecaprenyl-phosphate galactose phosphotransferase; TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.606 |
ACX97059.1 | ACX95351.1 | Hneap_2244 | Hneap_0496 | PFAM: NAD-dependent epimerase/dehydratase; KEGG: noc:Noc_2776 NAD-dependent epimerase/dehydratase. | KEGG: tgr:Tgr7_2083 undecaprenyl-phosphate galactose phosphotransferase; TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase. | 0.630 |
ACX97059.1 | ACX97062.1 | Hneap_2244 | Hneap_2247 | PFAM: NAD-dependent epimerase/dehydratase; KEGG: noc:Noc_2776 NAD-dependent epimerase/dehydratase. | Arsenate reductase-like protein; PFAM: arsenate reductase and related; KEGG: vap:Vapar_3763 arsenate reductase and related; Belongs to the ArsC family. | 0.638 |
ACX97059.1 | dapE | Hneap_2244 | Hneap_2246 | PFAM: NAD-dependent epimerase/dehydratase; KEGG: noc:Noc_2776 NAD-dependent epimerase/dehydratase. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.694 |
ACX97059.1 | murJ | Hneap_2244 | Hneap_2245 | PFAM: NAD-dependent epimerase/dehydratase; KEGG: noc:Noc_2776 NAD-dependent epimerase/dehydratase. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.775 |
ACX97062.1 | ACX97059.1 | Hneap_2247 | Hneap_2244 | Arsenate reductase-like protein; PFAM: arsenate reductase and related; KEGG: vap:Vapar_3763 arsenate reductase and related; Belongs to the ArsC family. | PFAM: NAD-dependent epimerase/dehydratase; KEGG: noc:Noc_2776 NAD-dependent epimerase/dehydratase. | 0.638 |
ACX97062.1 | dapE | Hneap_2247 | Hneap_2246 | Arsenate reductase-like protein; PFAM: arsenate reductase and related; KEGG: vap:Vapar_3763 arsenate reductase and related; Belongs to the ArsC family. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.936 |
ACX97062.1 | murJ | Hneap_2247 | Hneap_2245 | Arsenate reductase-like protein; PFAM: arsenate reductase and related; KEGG: vap:Vapar_3763 arsenate reductase and related; Belongs to the ArsC family. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.638 |
dapE | ACX97059.1 | Hneap_2246 | Hneap_2244 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | PFAM: NAD-dependent epimerase/dehydratase; KEGG: noc:Noc_2776 NAD-dependent epimerase/dehydratase. | 0.694 |
dapE | ACX97062.1 | Hneap_2246 | Hneap_2247 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Arsenate reductase-like protein; PFAM: arsenate reductase and related; KEGG: vap:Vapar_3763 arsenate reductase and related; Belongs to the ArsC family. | 0.936 |
dapE | murJ | Hneap_2246 | Hneap_2245 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.747 |
ftsI | ftsW | Hneap_0444 | Hneap_0449 | Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.996 |
ftsI | murA | Hneap_0444 | Hneap_0765 | Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.788 |
ftsI | murJ | Hneap_0444 | Hneap_2245 | Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.625 |
ftsW | ftsI | Hneap_0449 | Hneap_0444 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.996 |