STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACX97194.1PFAM: aminotransferase class-III; KEGG: bmj:BMULJ_05305 aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (462 aa)    
Predicted Functional Partners:
ACX96008.1
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: nmc:NMC0753 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.977
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.963
hemL
TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: tgr:Tgr7_2421 glutamate-1-semialdehyde-2,1-aminomutase.
  
  
 
0.926
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.770
ACX97188.1
PFAM: aminotransferase class-III; KEGG: mpt:Mpe_A1902 putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
     0.657
cysG
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
   
 0.656
ACX95796.1
PFAM: KR domain protein; Beta-ketoacyl synthase; Alcohol dehydrogenase GroES domain protein; short-chain dehydrogenase/reductase SDR; Acyl transferase; Alcohol dehydrogenase zinc-binding domain protein; phosphopantetheine-binding; NAD-dependent epimerase/dehydratase; KEGG: npu:Npun_F3360 beta-ketoacyl synthase.
    
 0.617
ACX96340.1
PFAM: KR domain protein; Acyl transferase; Beta-ketoacyl synthase; Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KEGG: neu:NE1389 putative type I polyketide synthase WcbR.
    
 0.609
ACX97192.1
PFAM: FAD dependent oxidoreductase; KEGG: mpt:Mpe_A1899 oxidoreductase.
 
    0.535
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.508
Your Current Organism:
Halothiobacillus neapolitanus
NCBI taxonomy Id: 555778
Other names: H. neapolitanus c2, Halothiobacillus neapolitanus ATCC 23641, Halothiobacillus neapolitanus c2, Halothiobacillus neapolitanus str. c2, Halothiobacillus neapolitanus strain c2
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