STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEA10491.12,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase. (220 aa)    
Predicted Functional Partners:
SEA35132.1
Riboflavin synthase alpha chain.
 
 
 0.992
SDZ96530.1
3,4-dihydroxy 2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
 
 0.981
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 0.953
moaA
Cyclic pyranopterin phosphate synthase; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
    
 0.806
SEA11995.1
Hypothetical protein; Catalyzes the dephosphorylation of 2-phosphoglycolate.
    
 0.788
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
  
  0.783
SDZ82843.1
BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase.
  
  
 0.703
SEA10510.1
Replication factor A1.
 
 
   0.687
SEA10529.1
Hypothetical protein.
 
     0.675
SEA10475.1
Thioredoxin.
       0.636
Your Current Organism:
Haloplanus vescus
NCBI taxonomy Id: 555874
Other names: CGMCC 1.8712, H. vescus, Haloplanus sp. RO5-8, Haloplanus vescus Cui et al. 2010, JCM 16055, strain RO5-8
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