STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEA37687.1ATP-binding cassette, subfamily B. (629 aa)    
Predicted Functional Partners:
SEA37703.1
PAS domain S-box-containing protein.
       0.773
SDZ75229.1
ABC-2 type transport system ATP-binding protein.
  
 
 0.657
dnaK
Molecular chaperone DnaK; Acts as a chaperone.
  
 0.657
SEA37771.1
ATPase family associated with various cellular activities (AAA); Belongs to the AAA ATPase family.
  
 
 0.652
SEA37670.1
Hypothetical protein.
       0.584
SEA23122.1
Tetratricopeptide repeat-containing protein.
  
 
 0.573
pan-2
Proteasome regulatory subunit; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S p [...]
  
 
  0.569
SEA37726.1
NADPH2:quinone reductase.
   
   0.569
pan
Proteasome regulatory subunit; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S p [...]
  
 
  0.565
SEA39678.1
Hypothetical protein.
    
 0.564
Your Current Organism:
Haloplanus vescus
NCBI taxonomy Id: 555874
Other names: CGMCC 1.8712, H. vescus, Haloplanus sp. RO5-8, Haloplanus vescus Cui et al. 2010, JCM 16055, strain RO5-8
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