STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFR59206.1Succinate dehydrogenase subunit D. (125 aa)    
Predicted Functional Partners:
SFR59197.1
Succinate dehydrogenase subunit C.
  
 0.999
SFR59216.1
Succinate dehydrogenase / fumarate reductase iron-sulfur subunit.
  
 0.999
SFR59227.1
Succinate dehydrogenase / fumarate reductase flavoprotein subunit.
  
 0.991
SFR51124.1
Succinate dehydrogenase subunit A.
  
 0.978
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.978
SFR35914.1
NADH-quinone oxidoreductase subunit C/D.
   
    0.966
SFR45081.1
NADH dehydrogenase subunit D.
   
    0.966
SFR69014.1
Cytochrome c oxidase subunit I+III; Belongs to the heme-copper respiratory oxidase family.
   
  
 0.912
sucD
succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.856
fumC
Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 
 0.798
Your Current Organism:
Halogeometricum limi
NCBI taxonomy Id: 555875
Other names: CGMCC 1.8711, H. limi, Halobacteriaceae archaeon RO1-6, Halogeometricum limi (Cui et al. 2010) Qiu et al. 2013, Halosarcina limi, Halosarcina limi Cui et al. 2010, JCM 16054, strain RO1-6
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.