STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFR64117.1Cell division control protein 6; Involved in regulation of DNA replication. (426 aa)    
Predicted Functional Partners:
SFR33766.1
Intein C-terminal splicing region/intein N-terminal splicing region.
  
 0.902
SFR47385.1
DNA polymerase I.
  
 0.868
priL
DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
  
 0.777
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
  
 
 0.757
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
   
 0.682
SFR60018.1
Putative nucleotide binding protein.
  
     0.673
SFR68795.1
Uncharacterized protein.
  
     0.658
eif5a
Translation initiation factor 5A precursor (eIF-5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
     0.657
SFR37577.1
Hypothetical protein; Involved in DNA damage repair.
  
     0.648
rpl18e
Large subunit ribosomal protein L18e; Belongs to the eukaryotic ribosomal protein eL18 family.
  
     0.611
Your Current Organism:
Halogeometricum limi
NCBI taxonomy Id: 555875
Other names: CGMCC 1.8711, H. limi, Halobacteriaceae archaeon RO1-6, Halogeometricum limi (Cui et al. 2010) Qiu et al. 2013, Halosarcina limi, Halosarcina limi Cui et al. 2010, JCM 16054, strain RO1-6
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