Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
macBMacrolide ABC transporter ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (239 aa)    
Predicted Functional Partners:
macB_4
ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
AQM14689.1
Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.992
AQM14692.1
Efflux transporter periplasmic adaptor subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.940
AQM14691.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.900
AQM12882.1
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
0.846
AQM12004.1
Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.673
AQM14605.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.673
mltC
Lytic murein transglycosylase; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.
    
 
 0.670
Slt
Lytic murein transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.632
LolC
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.631
Your Current Organism:
Vibrio anguillarum
NCBI taxonomy Id: 55601
Other names: ATCC 19264, Achromobacter ichthyodermis, CAIM 696, CCUG 47265, CIP 63.36, DSM 21597, IFO 13266, LMG 4437, LMG:4437, Listonella anguillara, Listonella anguillarum, NBRC 13266, NCCB 72050, NCIMB 6, NCTC 12159, Pseudomonas ichthyodermis, V. anguillarum, Vibrio ichthyodermis, Vibrio piscium, Vibrio piscium var. japonicus
Server load: low (8%) [HD]