STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
oadAOxaloacetate decarboxylase alpha subunit. (599 aa)    
Predicted Functional Partners:
EEO25253.1
acetyl-CoA carboxylase subunit A.
 
 0.999
accC
acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.999
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 
 0.990
accA
acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
 0.975
EEO26649.1
biotin--[acetyl-CoA-carboxylase] ligase.
 
 
 0.951
fabH
3-oxoacyl-(acyl carrier protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
 
 0.947
EEO26626.1
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
    
 0.939
ppsA
Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
  
 
 0.933
EEO26836.1
4Fe-4S binding domain protein.
     
 0.917
EEO25614.1
Putative malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)).
    
 0.915
Your Current Organism:
Helicobacter winghamensis
NCBI taxonomy Id: 556267
Other names: H. winghamensis ATCC BAA-430, Helicobacter winghamensis ATCC BAA-430, Helicobacter winghamensis str. ATCC BAA-430, Helicobacter winghamensis strain ATCC BAA-430
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.