STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APF39674.1Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (491 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 0.998
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
 
 0.996
APF39676.1
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.973
APF41597.1
Chlorite dismutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.861
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
   
 0.844
APF39678.1
Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family.
 
  
 0.772
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.760
APF41603.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.702
APF39677.1
Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
  
 0.628
APF41404.1
C-type cytochrome biogenesis protein CcsB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.500
Your Current Organism:
Neomicrococcus aestuarii
NCBI taxonomy Id: 556325
Other names: JCM 16364, KCTC 19557, Micrococcus sp. DY66, N. aestuarii, NBRC 109060, Neomicrococcus aestuarii (Baik et al. 2011) Prakash et al. 2015, Zhihengliuella aestuarii, Zhihengliuella aestuarii Baik et al. 2011, strain DY66
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