STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHATR_33295Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1186 aa)    
Predicted Functional Partners:
B7G865_PHATC
Predicted protein.
    
 0.999
NURF-55
Chromatin assembly factor subunit c.
    
 
 0.772
B7FTC2_PHATC
Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
    
 0.705
B7G914_PHATC
Predicted protein.
    
 0.705
B7GDV3_PHATC
Predicted protein.
    
 0.705
H3-1c
Histone H3; Belongs to the histone H3 family.
    
 
 0.690
B7FX13_PHATC
Predicted protein.
    
 
 0.690
H3.3
Histone H3; Belongs to the histone H3 family.
    
 
 0.690
B7GE11_PHATC
Predicted protein.
    
 
 0.690
H4-1b
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.630
Your Current Organism:
Phaeodactylum tricornutum
NCBI taxonomy Id: 556484
Other names: P. tricornutum CCAP 1055/1, Phaeodactylum tricornutum CCAP 1055/1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.