PHATR_44117 protein (Phaeodactylum tricornutum)

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

PHATR_44117

Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family. (532 aa)

Predicted Functional Partners:

B7FW27_PHATC

0.999

B7FU52_PHATC

0.990

B7FVP6_PHATC

0.990

B7FZD8_PHATC

0.990

B7FUJ6_PHATC

0.949

DPM1

0.770

B7FZ16_PHATC

0.770

B7G4N6_PHATC

0.625

B7FU21_PHATC

0.610

B7G3V4_PHATC

0.608

Your Current Organism:

Phaeodactylum tricornutum

NCBI taxonomy Id: 556484
Other names: P. tricornutum CCAP 1055/1, Phaeodactylum tricornutum CCAP 1055/1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7FU21_PHATC	B7FU52_PHATC	B7FU21	B7FU52	Mannosyltransferase.	Mannosyltransferase.	0.990
B7FU21_PHATC	B7FUJ6_PHATC	B7FU21	B7FUJ6	Mannosyltransferase.	Mannosyltransferase.	0.998
B7FU21_PHATC	B7FVP6_PHATC	B7FU21	B7FVP6	Mannosyltransferase.	Dolichol phosphate glucosyltransferase.	0.910
B7FU21_PHATC	B7FW27_PHATC	B7FU21	B7FW27	Mannosyltransferase.	Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family.	0.588
B7FU21_PHATC	B7FZ16_PHATC	B7FU21	B7FZ16	Mannosyltransferase.	Predicted protein.	0.776
B7FU21_PHATC	B7FZD8_PHATC	B7FU21	B7FZD8	Mannosyltransferase.	Predicted protein.	0.910
B7FU21_PHATC	B7G3V4_PHATC	B7FU21	B7G3V4	Mannosyltransferase.	Beta-mannosyltransferase.	0.602
B7FU21_PHATC	B7G4N6_PHATC	B7FU21	B7G4N6	Mannosyltransferase.	UDP-glucose:glycoprotein glucosyltransferase.	0.475
B7FU21_PHATC	DPM1	B7FU21	B7FWX4	Mannosyltransferase.	Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.	0.776
B7FU21_PHATC	PHATR_44117	B7FU21	B5Y5E2	Mannosyltransferase.	Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family.	0.610
B7FU52_PHATC	B7FU21_PHATC	B7FU52	B7FU21	Mannosyltransferase.	Mannosyltransferase.	0.990
B7FU52_PHATC	B7FUJ6_PHATC	B7FU52	B7FUJ6	Mannosyltransferase.	Mannosyltransferase.	0.998
B7FU52_PHATC	B7FVP6_PHATC	B7FU52	B7FVP6	Mannosyltransferase.	Dolichol phosphate glucosyltransferase.	0.917
B7FU52_PHATC	B7FW27_PHATC	B7FU52	B7FW27	Mannosyltransferase.	Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family.	0.689
B7FU52_PHATC	B7FZ16_PHATC	B7FU52	B7FZ16	Mannosyltransferase.	Predicted protein.	0.761
B7FU52_PHATC	B7FZD8_PHATC	B7FU52	B7FZD8	Mannosyltransferase.	Predicted protein.	0.917
B7FU52_PHATC	B7G3V4_PHATC	B7FU52	B7G3V4	Mannosyltransferase.	Beta-mannosyltransferase.	0.607
B7FU52_PHATC	DPM1	B7FU52	B7FWX4	Mannosyltransferase.	Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.	0.975
B7FU52_PHATC	PHATR_44117	B7FU52	B5Y5E2	Mannosyltransferase.	Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family.	0.990
B7FUJ6_PHATC	B7FU21_PHATC	B7FUJ6	B7FU21	Mannosyltransferase.	Mannosyltransferase.	0.998

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

39

average node degree:

7.09

avg. local clustering coefficient:

0.845

expected number of edges:

10

PPI enrichment p-value:

6.32e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006810

Transport

11 of 644

1.0

1.22

1.78e-08

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0036094

Small molecule binding

8 of 978

0.68

0.42

0.0283

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030288

Outer membrane-bounded periplasmic space

3 of 25

1.84

1.35

0.0019

GO:0005886

Plasma membrane

9 of 1856

0.45

0.33

0.0139

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:8072

Mixed, incl. ABC transporter, permease protein, BtuC-like, and Periplasmic binding protein

10 of 26

2.35

8.42

4.14e-20

CL:8071

Mixed, incl. ABC transporter, permease protein, BtuC-like, and Periplasmic binding protein

11 of 36

2.25

8.41

1.33e-21

CL:8073

ABC transporter, permease protein, BtuC-like, and Periplasmic binding protein

9 of 20

2.42

8.04

2.60e-18

CL:8074

ABC transporter, permease protein, BtuC-like, and Periplasmic binding protein

5 of 12

2.38

4.12

6.41e-09

CL:8098

Mixed, incl. FecCD transport family, and Transmembrane secretion effector

4 of 7

2.52

3.44

2.75e-07

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0030288

Outer membrane-bounded periplasmic space

3 of 45

1.59

1.05

0.0057

GOCC:0005886

Plasma membrane

8 of 615

0.88

0.77

0.00035

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0067

ATP-binding

6 of 323

1.03

0.85

0.0014

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01497

Periplasmic binding protein

3 of 8

2.34

1.77

0.00047

PF01032

FecCD transport family

2 of 8

2.16

0.73

0.0458

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR017871

ABC transporter-like, conserved site

6 of 92

1.58

1.96

9.05e-06

IPR002491

ABC transporter periplasmic binding domain

3 of 8

2.34

1.87

0.00029

IPR003439

ABC transporter-like, ATP-binding domain

6 of 111

1.5

1.8

1.33e-05

IPR003593

AAA+ ATPase domain

6 of 150

1.37

1.49

5.00e-05

IPR027417

P-loop containing nucleoside triphosphate hydrolase

6 of 310

1.05

0.84

0.0020

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00382

ATPases associated with a variety of cellular activities

6 of 144

1.38

1.68

8.74e-06

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