STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LONM_PHATCLon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (882 aa)    
Predicted Functional Partners:
B7FQF0_PHATC
Predicted protein.
   
 0.821
B7FYH6_PHATC
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
  
 0.795
B7G710_PHATC
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
  
 0.795
B7GBW5_PHATC
Predicted protein; Belongs to the AAA ATPase family.
  
 
 0.711
B7G3N1_PHATC
Predicted protein.
   
 
 0.705
PHATR_33525
Predicted protein.
  
  
 0.699
B7FVS6_PHATC
Predicted protein.
 
 
 0.693
B7FQJ9_PHATC
Predicted protein.
  
  
 0.679
groL
60 kDa chaperonin, chloroplastic; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.672
CPN60_1
Mitochondria-targeted chaperonin; Belongs to the chaperonin (HSP60) family.
  
 0.672
Your Current Organism:
Phaeodactylum tricornutum
NCBI taxonomy Id: 556484
Other names: P. tricornutum CCAP 1055/1, Phaeodactylum tricornutum CCAP 1055/1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.