STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HemE_1Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (431 aa)    
Predicted Functional Partners:
PPO
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
 
  
 0.890
hemC
Hydroxymethylbilane synthase.
 
 
 0.882
HemF_3
Coproporphyrinogen oxidase.
  
 0.863
B7FXE4_PHATC
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
 
  
 0.861
B7FSN7_PHATC
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
 
 0.798
HemA
Glutamyl-tRNA reductase; Belongs to the glutamyl-tRNA reductase family.
  
  
 0.768
HemF_2
Coproporphyrinogen oxidase. coproporphyrinogen III oxidase. coproporphyrinogenase.
  
 
 0.737
HemF_1
Coproporphyrinogen III oxidase.
  
 
 0.737
B7FVQ7_PHATC
Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.
      
 0.703
CMK
4-diphosphocytidyl-2c-methyl-d-erythritol kinase.
   
  
 0.696
Your Current Organism:
Phaeodactylum tricornutum
NCBI taxonomy Id: 556484
Other names: P. tricornutum CCAP 1055/1, Phaeodactylum tricornutum CCAP 1055/1
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