STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B7G334_PHATCDNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (489 aa)    
Predicted Functional Partners:
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.855
B7G7W7_PHATC
Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.
    
 0.844
PHATR_46865
Predicted protein.
  
 0.831
B7FS62_PHATC
Predicted protein.
  
 0.821
B7G0D2_PHATC
Predicted protein.
  
 0.821
PHATR_10585
Predicted protein.
  
 
 0.811
B7G2F2_PHATC
Predicted protein.
  
 
 0.811
B7G5J8_PHATC
Predicted protein.
   
 0.808
B7G202_PHATC
Predicted protein.
  
 0.795
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.795
Your Current Organism:
Phaeodactylum tricornutum
NCBI taxonomy Id: 556484
Other names: P. tricornutum CCAP 1055/1, Phaeodactylum tricornutum CCAP 1055/1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.