STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N303_05393E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1739 aa)    
Predicted Functional Partners:
N303_02431
E3 ubiquitin-protein ligase TRIP12.
   
 0.990
N303_02186
Polyubiquitin-C.
   
 0.809
N303_10928
Ubiquitin-conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.802
N303_07992
Ubiquitin-conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.802
N303_11545
Ubiquitin-40S ribosomal protein S27a.
   
 0.752
N303_13744
E3 ubiquitin-protein ligase listerin.
   
 0.688
N303_15335
Ubiquitin-60S ribosomal protein L40.
    
  0.682
N303_06642
Protein KIBRA.
   
 0.671
N303_14544
Baculoviral IAP repeat-containing protein 6.
   
 
 0.666
N303_00350
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.666
Your Current Organism:
Cuculus canorus
NCBI taxonomy Id: 55661
Other names: C. canorus, common cuckoo
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.