STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N303_09514Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)    
Predicted Functional Partners:
N303_06423
Interferon gamma receptor 1.
    
 0.995
N303_13720
Interferon gamma receptor 2.
  
 
 0.992
N303_10777
Sushi domain-containing protein.
   
 
 0.927
N303_12636
Interferon lambda receptor 1.
  
 
 0.924
N303_09101
Interleukin-7 receptor subunit alpha.
  
 
 0.922
N303_13721
Interferon alpha/beta receptor 1.
     
 0.913
N303_09452
Interleukin-23 receptor.
   
 
 0.911
N303_06774
Tyrosine-protein kinase.
   
 
 0.908
N303_06584
Interleukin-21 receptor.
  
 
 0.902
N303_09876
Interleukin-2 receptor subunit beta.
   
 
 0.898
Your Current Organism:
Cuculus canorus
NCBI taxonomy Id: 55661
Other names: C. canorus, common cuckoo
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.