STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N303_08723Dynein heavy chain 10, axonemal. (4032 aa)    
Predicted Functional Partners:
N303_08565
Dynein intermediate chain 2, axonemal.
  
 0.915
PAFAH1B1
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.
    
 0.887
N303_09917
Dynein light chain.
    
 0.880
N303_01432
Dynein light chain roadblock-type 1.
    
 0.844
N303_10590
Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.
    
 0.832
N303_14880
Dynactin subunit 2.
    
 0.832
N303_10592
Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.
    
 0.832
N303_07773
TBC1 domain family member 31.
    
 0.824
N303_05240
Dynactin subunit 1.
   
 0.812
N303_05241
Dynactin subunit 1.
   
 0.812
Your Current Organism:
Cuculus canorus
NCBI taxonomy Id: 55661
Other names: C. canorus, common cuckoo
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.