STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N303_00148Tryptophan 5-hydroxylase 1. (444 aa)    
Predicted Functional Partners:
N303_10936
Pterin-4-alpha-carbinolamine dehydratase 2.
  
 0.941
N303_05812
Pterin-4-alpha-carbinolamine dehydratase.
  
 0.941
N303_04479
Tryptophan 5-hydroxylase 2.
  
 
 
0.897
N303_07331
Aromatic-L-amino-acid decarboxylase.
   
 0.893
N303_05313
Sepiapterin reductase.
  
 
 0.881
N303_05443
Indoleamine 2,3-dioxygenase 2.
   
 
 0.880
N303_02782
Dihydropteridine reductase.
   
 0.878
TDO2
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
  
 
 0.876
N303_13997
Dihydrofolate reductase.
     
 0.835
N303_05536
Phenylalanine-4-hydroxylase.
  
  
 
0.832
Your Current Organism:
Cuculus canorus
NCBI taxonomy Id: 55661
Other names: C. canorus, common cuckoo
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.