STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N303_09313HORMA domain-containing protein 2. (284 aa)    
Predicted Functional Partners:
N303_09911
Meiotic recombination protein DMC1/LIM15; Belongs to the RecA family.
   
 
 0.667
N303_06800
Pachytene checkpoint protein 2; Belongs to the AAA ATPase family.
   
 
 0.606
N303_14635
Fanconi anemia group M protein.
      
 0.604
N303_10028
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
   
 
 0.585
N303_12457
DNA repair protein RAD51 3.
   
 
 0.535
N303_10027
Protein CASC5.
   
 
 0.535
N303_11354
Structural maintenance of chromosomes protein 3.
    
 
 0.535
N303_07126
DNA repair protein RAD51 2.
   
 
 0.534
N303_10194
Serine/threonine-protein kinase DCLK1.
    
 
 0.510
N303_10192
Serine/threonine-protein kinase DCLK1; Belongs to the protein kinase superfamily.
    
 
 0.510
Your Current Organism:
Cuculus canorus
NCBI taxonomy Id: 55661
Other names: C. canorus, common cuckoo
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.