STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N303_06392Nibrin. (750 aa)    
Predicted Functional Partners:
N303_01984
Double-strand break repair protein MRE11; Belongs to the MRE11/RAD32 family.
    
  0.963
N303_10908
DNA repair protein RAD50.
    
  0.945
N303_15118
GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.
   
 
 0.861
N303_08864
Mannosyltransferase.
     
 0.857
N303_14585
Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
   
 
 0.839
N303_02913
Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.
    
 0.835
N303_06075
Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family.
     
 0.809
N303_14635
Fanconi anemia group M protein.
   
 
  0.743
N303_02440
Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family.
   
 
  0.677
N303_03540
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A.
   
 
 0.674
Your Current Organism:
Cuculus canorus
NCBI taxonomy Id: 55661
Other names: C. canorus, common cuckoo
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.