STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N303_14195F-box/WD repeat-containing protein 4. (323 aa)    
Predicted Functional Partners:
N303_10926
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.841
N303_04532
Cullin-3; Belongs to the cullin family.
    
  0.806
N303_05153
CDK2-associated and cullin domain-containing protein 1; Belongs to the cullin family.
    
  0.762
N303_14197
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
 
    
 0.730
N303_07498
Thioredoxin domain-containing protein 9.
    
   0.653
N303_00082
T-complex protein 1 subunit epsilon; Belongs to the TCP-1 chaperonin family.
    
  0.651
N303_01204
T-complex protein 1 subunit delta; Belongs to the TCP-1 chaperonin family.
    
 0.639
N303_11796
T-complex protein 1 subunit gamma; Belongs to the TCP-1 chaperonin family.
    
  0.608
N303_05306
T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
    
  0.601
N303_13741
T-complex protein 1 subunit theta; Belongs to the TCP-1 chaperonin family.
    
  0.589
Your Current Organism:
Cuculus canorus
NCBI taxonomy Id: 55661
Other names: C. canorus, common cuckoo
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.