STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N303_05436Histone-lysine N-methyltransferase NSD3. (655 aa)    
Predicted Functional Partners:
N303_03092
Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific.
 
 
  
 0.905
N303_02599
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1.
    
 0.856
N303_15005
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
    
 0.851
N303_07569
Calmodulin-lysine N-methyltransferase.
     
 0.836
N303_05431
Set1/Ash2 histone methyltransferase complex subunit ASH2.
    
 0.786
N303_00267
Retinoblastoma-binding protein 5.
    
 0.786
N303_11724
Polycomb protein EED.
   
 0.768
N303_07529
SET-binding protein.
   
 
 0.747
N303_09764
Histone-lysine N-methyltransferase SETD2.
   
 
0.746
N303_13201
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.736
Your Current Organism:
Cuculus canorus
NCBI taxonomy Id: 55661
Other names: C. canorus, common cuckoo
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.