STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lreu_1568Phosphate ABC transporter substrate-binding protein, PhoT family; TIGRFAM: phosphate binding protein; PFAM: extracellular solute-binding protein, family 1; TC 3.A.1.7.1. (290 aa)    
Predicted Functional Partners:
pstB
Phosphate ABC transporter ATP-binding protein, PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
 0.999
Lreu_1566
TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; TC 3.A.1.7.1.
 
 0.999
Lreu_1567
Phosphate ABC transporter membrane protein 1, PhoT family; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
 0.999
Lreu_1564
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
 
  
 0.981
Lreu_1874
PFAM: GCN5-related N-acetyltransferase.
      0.716
Lreu_1569
Putative two component transcriptional regulator, winged helix family; PFAM: transcriptional regulator domain protein.
 
  
 0.669
prfB
Bacterial peptide chain release factor 2 (bRF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
 
    0.646
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.603
Lreu_0517
Amino acid ABC transporter substrate-binding protein, PAAT family; PFAM: extracellular solute-binding protein, family 3; TC 3.A.1.3.-.
  
  
 0.499
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
   
    0.468
Your Current Organism:
Lactobacillus reuteri
NCBI taxonomy Id: 557436
Other names: L. reuteri DSM 20016, Lactobacillus reuteri DSM 20016, Lactobacillus reuteri str. DSM 20016, Lactobacillus reuteri strain DSM 20016
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