STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lreu_1680Transcriptional regulator; PFAM: ROK family protein. (300 aa)    
Predicted Functional Partners:
Lreu_1681
Branched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids.
       0.697
Lreu_1682
PFAM: transposase IS200-family protein.
       0.500
Lreu_1086
TIGRFAM: PTS system, glucose subfamily, IIA subunit; sugar (Glycoside-Pentoside-Hexuronide) transporter; PFAM: sugar-specific permease, EIIA 1 domain; TC 4.A.1.
  
  
 0.470
Lreu_1768
TIGRFAM: PTS system, glucose subfamily, IIA subunit; sugar (Glycoside-Pentoside-Hexuronide) transporter; PFAM: sugar-specific permease, EIIA 1 domain; TC 4.A.1.
  
  
 0.470
mprF-2
Protein of unknown function DUF470; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
     
 0.433
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
  
 0.422
Your Current Organism:
Lactobacillus reuteri
NCBI taxonomy Id: 557436
Other names: L. reuteri DSM 20016, Lactobacillus reuteri DSM 20016, Lactobacillus reuteri str. DSM 20016, Lactobacillus reuteri strain DSM 20016
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