STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lreu_1792TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. (307 aa)    
Predicted Functional Partners:
Lreu_1791
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-serine, forming acetyl-L-serine; Belongs to the MetA family.
 
  
 0.988
Lreu_0293
Cystathionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class-III.
 
 0.976
cysS
TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase, class Ia, DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase, class Ia-like; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.924
Lreu_1912
PFAM: aminotransferase, class I and II.
    
 0.911
Lreu_1553
Cystathionine beta-synthase (acetylserine-dependent); PFAM: Pyridoxal-5'-phosphate-dependent protein, beta subunit.
  
  
 
0.908
luxS
Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
 
 0.871
Lreu_1883
Lysyl aminopeptidase, Metallo peptidase, MEROPS family M01; PFAM: Peptidase M1, membrane alanine aminopeptidase-like.
    
 0.819
Lreu_1042
PFAM: homocysteine S-methyltransferase.
     
 0.817
Lreu_1081
PFAM: Methionine synthase, vitamin-B12 independent; Cobalamin-independent synthase MetE, N-terminal domain protein.
   
 
 0.817
Lreu_1870
PFAM: Methionine synthase, vitamin-B12 independent.
   
 
 0.817
Your Current Organism:
Lactobacillus reuteri
NCBI taxonomy Id: 557436
Other names: L. reuteri DSM 20016, Lactobacillus reuteri DSM 20016, Lactobacillus reuteri str. DSM 20016, Lactobacillus reuteri strain DSM 20016
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