Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
KZX17596.1Hypothetical protein. (137 aa)    
Predicted Functional Partners:
comB
Putative 2-phosphosulfolactate phosphatase.
   
    0.732
KZX17597.1
Hypothetical protein.
 
     0.642
tfe
Transcription initiation factor E subunit alpha; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elo [...]
  
     0.627
nusA
Hypothetical protein; Participates in transcription termination. Belongs to the NusA family.
  
     0.541
gch3
GTP cyclohydrolase III; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family.
  
     0.522
thrB_2
Homoserine kinase.
  
     0.498
rps17e
30S ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family.
       0.493
fbiB_3
Coenzyme F420:L-glutamate ligase.
  
    0.461
KZX15901.1
H/ACA RNA-protein complex component Cbf5p.
 
     0.460
KZX10712.1
Hypothetical protein.
  
     0.453
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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