Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fdhFFormate dehydrogenase H. (706 aa)    
Predicted Functional Partners:
KZX17422.1
Coenzyme F420-reducing hydrogenase subunit beta.
 
 0.999
KZX17211.1
Methyl-viologen-reducing hydrogenase, delta subunit.
   
 0.988
ndhI_7
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
   
 0.983
lutA_2
Lactate utilization protein A.
   
 0.971
KZX11758.1
Succinate dehydrogenase/fumarate reductase iron-sulfur subunit.
   
 0.971
fdnG
Formate dehydrogenase, nitrate-inducible, major subunit precursor.
 
 
0.969
fhcA
Formyltransferase/hydrolase complex Fhc subunit A.
  
 0.968
KZX17433.1
Molybdopterin dinucleotide binding domain protein.
   
  0.956
ndhI_1
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic.
   
  0.955
cooF_2
Iron-sulfur protein.
    
 0.942
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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