hemC protein (Methanobrevibacter filiformis)

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[Homology]

Score

hemC

Porphobilinogen deaminase. (240 aa)

Predicted Functional Partners:

KZX15373.1

0.999

hemB

0.999

sumT

0.996

hemA

0.987

hemL

0.953

sirC

0.870

bchI

0.820

iolX

0.740

pyrE_1

0.737

glyA

0.700

Your Current Organism:

Methanobrevibacter filiformis

NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KZX15373.1	hemA	MBFIL_06740	MBFIL_11980	uroporphyrinogen-III synthase.	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).	0.864
KZX15373.1	hemB	MBFIL_06740	MBFIL_10400	uroporphyrinogen-III synthase.	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	0.984
KZX15373.1	hemC	MBFIL_06740	MBFIL_02170	uroporphyrinogen-III synthase.	Porphobilinogen deaminase.	0.999
KZX15373.1	hemL	MBFIL_06740	MBFIL_17790	uroporphyrinogen-III synthase.	Glutamate-1-semialdehyde 2,1-aminomutase.	0.889
KZX15373.1	sirC	MBFIL_06740	MBFIL_11970	uroporphyrinogen-III synthase.	Precorrin-2 dehydrogenase.	0.859
KZX15373.1	sumT	MBFIL_06740	MBFIL_06730	uroporphyrinogen-III synthase.	uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family.	0.999
bchI	hemA	MBFIL_05970	MBFIL_11980	Magnesium-chelatase 38 kDa subunit.	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).	0.731
bchI	hemB	MBFIL_05970	MBFIL_10400	Magnesium-chelatase 38 kDa subunit.	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	0.693
bchI	hemC	MBFIL_05970	MBFIL_02170	Magnesium-chelatase 38 kDa subunit.	Porphobilinogen deaminase.	0.820
glyA	hemA	MBFIL_16020	MBFIL_11980	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family.	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).	0.485
glyA	hemC	MBFIL_16020	MBFIL_02170	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family.	Porphobilinogen deaminase.	0.700
glyA	hemL	MBFIL_16020	MBFIL_17790	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family.	Glutamate-1-semialdehyde 2,1-aminomutase.	0.481
hemA	KZX15373.1	MBFIL_11980	MBFIL_06740	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).	uroporphyrinogen-III synthase.	0.864
hemA	bchI	MBFIL_11980	MBFIL_05970	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).	Magnesium-chelatase 38 kDa subunit.	0.731
hemA	glyA	MBFIL_11980	MBFIL_16020	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family.	0.485
hemA	hemB	MBFIL_11980	MBFIL_10400	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	0.938
hemA	hemC	MBFIL_11980	MBFIL_02170	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).	Porphobilinogen deaminase.	0.987
hemA	hemL	MBFIL_11980	MBFIL_17790	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).	Glutamate-1-semialdehyde 2,1-aminomutase.	0.999
hemA	sirC	MBFIL_11980	MBFIL_11970	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).	Precorrin-2 dehydrogenase.	0.978
hemA	sumT	MBFIL_11980	MBFIL_06730	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).	uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family.	0.878