STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hoxH_1NAD-reducing hydrogenase HoxS subunit beta; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (475 aa)    
Predicted Functional Partners:
KZX17211.1
Methyl-viologen-reducing hydrogenase, delta subunit.
 
 0.999
hoxY
NAD-reducing hydrogenase HoxS subunit delta.
 
 0.999
ndhI_7
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
 0.999
KZX11758.1
Succinate dehydrogenase/fumarate reductase iron-sulfur subunit.
  
 0.997
lutA_2
Lactate utilization protein A.
  
 0.996
hyfA
Hydrogenase-4 component A.
  
 
 0.992
hydA
Periplasmic [Fe] hydrogenase large subunit.
 
 0.985
hypA
Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.978
KZX11480.1
Coenzyme F420-reducing hydrogenase subunit beta.
 
 0.971
mtrA
Tetrahydromethanopterin S-methyltransferase subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family.
     
 0.963
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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