STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hyfAHydrogenase-4 component A. (411 aa)    
Predicted Functional Partners:
hoxY
NAD-reducing hydrogenase HoxS subunit delta.
  
 
 0.993
hoxH_1
NAD-reducing hydrogenase HoxS subunit beta; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
 
 0.992
KZX17211.1
Methyl-viologen-reducing hydrogenase, delta subunit.
  
 
 0.972
KZX11758.1
Succinate dehydrogenase/fumarate reductase iron-sulfur subunit.
  
 
 0.968
ndhI_7
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
  
 
 0.964
fhcA
Formyltransferase/hydrolase complex Fhc subunit A.
    
 
 0.926
lutA_2
Lactate utilization protein A.
   
 
 0.917
nuoI
NADH-quinone oxidoreductase subunit I.
  
 
0.887
fdnG
Formate dehydrogenase, nitrate-inducible, major subunit precursor.
  
   0.824
ttrB
Tetrathionate reductase subunit B precursor.
  
 
0.766
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.