STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hypCHydrogenase isoenzymes formation protein HypC. (85 aa)    
Predicted Functional Partners:
hypD
Hydrogenase expression/formation protein HypD.
 
 
 0.989
hypE
Hydrogenase expression/formation protein HypE.
 
 
 0.979
hypF
Carbamoyltransferase HypF.
 
 
 0.937
hypB
Hydrogenase isoenzymes nickel incorporation protein HypB.
  
  
 0.917
hypA
Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.886
nac
Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
       0.578
hoxH_2
NAD-reducing hydrogenase HoxS subunit beta; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.568
hoxH_1
NAD-reducing hydrogenase HoxS subunit beta; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.559
mobA_1
Molybdenum cofactor guanylyltransferase.
 
     0.537
hyaD
Hydrogenase 1 maturation protease.
  
  
 0.532
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.