Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
hycE_1Formate hydrogenlyase subunit 5 precursor; Belongs to the complex I 49 kDa subunit family. (375 aa)    
Predicted Functional Partners:
hycG_1
Formate hydrogenlyase subunit 7.
 
 
 0.997
hycG_2
Formate hydrogenlyase subunit 7.
 
 
 0.991
mrpD
Na(+)/H(+) antiporter subunit D.
 
 
 0.971
nuoH
NADH-quinone oxidoreductase subunit H.
 
 
 0.965
ndhA
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic.
 
 
 0.913
KZX13993.1
Putative monovalent cation/H+ antiporter subunit E.
 
 
 0.878
hypB
Hydrogenase isoenzymes nickel incorporation protein HypB.
   
 
 0.849
KZX17067.1
Hypothetical protein.
     
 0.817
ndhI_4
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic.
  
 
 0.803
hypA
Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
 
 0.754
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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