STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KZX16987.1Hypothetical protein. (223 aa)    
Predicted Functional Partners:
trpS
tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp).
       0.877
thrC
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
     
 0.789
KZX10447.1
Hypothetical protein; Belongs to the UPF0179 family.
 
   
 0.742
egsA
Glycerol-1-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
  
  
 0.738
KZX12635.1
Hypothetical protein.
     
 0.735
KZX16985.1
tRNA-splicing endonuclease subunit alpha.
 
     0.687
KZX14110.1
Hydroxymethylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
       0.671
argS
arginine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.671
proS
proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
       0.555
KZX10640.1
DNA-binding transcriptional regulator IlvY.
 
    0.443
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.