STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KZX16967.1TraB family protein. (386 aa)    
Predicted Functional Partners:
KZX16968.1
Hypothetical protein.
       0.867
comB
Putative 2-phosphosulfolactate phosphatase.
       0.728
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
       0.671
KZX11765.1
Peptidase family M50.
       0.671
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
   0.664
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
       0.647
rnhC
Ribonuclease HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
   
   0.538
frdA
Fumarate reductase flavoprotein subunit.
    
   0.535
ndhI_4
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic.
    
   0.535
lcfB_1
long-chain-fatty-acid--CoA ligase.
    
   0.518
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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