Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nfo_2Endonuclease 4. (246 aa)    
Predicted Functional Partners:
paaK_1
Phenylacetate-coenzyme A ligase.
     
 0.650
iolX
Scyllo-inositol 2-dehydrogenase.
  
 
 0.624
rbsK
Ribokinase.
 
 
 0.560
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
  0.538
fae
5,6,7,8-tetrahydromethanopterin hydro-lyase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family.
  
 
  0.513
pheA
Prephenate dehydratase.
 
  
 0.507
nfo_3
Putative endonuclease 4.
    
 0.503
fucA
L-fuculose phosphate aldolase.
    
 0.496
adoK
Adenosine kinase; Belongs to the carbohydrate kinase PfkB family.
  
 
 0.490
KZX12311.1
Putative inner membrane protein.
       0.476
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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