Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
kynB_1Kynurenine formamidase. (119 aa)    
Predicted Functional Partners:
kynB_2
Kynurenine formamidase.
  
     0.493
accC
Biotin carboxylase.
    
  0.489
ttdA
L(+)-tartrate dehydratase subunit alpha.
    
  0.488
ttdB
L(+)-tartrate dehydratase subunit beta.
     
  0.484
cfiA
2-oxoglutarate carboxylase large subunit.
     
  0.484
fdhF
Formate dehydrogenase H.
    
  0.455
KZX10113.1
Fumarate hydratase.
    
  0.448
fumB
Fumarate hydratase class I, anaerobic.
     
  0.444
sufS
Cysteine desulfurase SufS.
  
 
  0.442
hddC
D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase.
     
 0.431
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
Server load: medium (80%) [HD]