Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
bioYBiotin transporter BioY. (205 aa)    
Predicted Functional Partners:
ecfA3
Energy-coupling factor transporter ATP-binding protein EcfA3; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
   
 0.982
nikQ
Nickel transport protein NikQ.
 
 0.952
KZX14935.1
Hypothetical protein.
 
 
  0.906
cbiQ
Cobalt transport protein CbiQ.
  
 0.880
birA
Bifunctional ligase/repressor BirA.
 
   
 0.854
drrA
Daunorubicin/doxorubicin resistance ATP-binding protein DrrA.
 
  
 0.612
mtrB
Tetrahydromethanopterin S-methyltransferase subunit B; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
      
 0.606
cobQ_2
Cobyric acid synthase.
       0.565
bioB
Biotin synthase.
  
  
 0.561
KZX12219.1
Hypothetical protein; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain.
      
 0.448
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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