Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KZX14596.1Hypothetical protein. (108 aa)    
Predicted Functional Partners:
selA
L-seryl-tRNA(Sec) selenium transferase.
  
    0.942
KZX14595.1
PRC-barrel domain protein.
       0.841
KZX11642.1
Methyl-coenzyme M reductase operon protein C.
    
   0.802
KZX11644.1
Hypothetical protein; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
   
   0.794
KZX11643.1
Methyl-coenzyme M reductase gamma subunit.
   
   0.783
KZX11640.1
Hypothetical protein; Methyl-coenzyme M reductase beta subunit, C-terminal domain.
   
   0.776
folE2
GTP cyclohydrolase FolE2; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
       0.660
KZX17300.1
Methyl-coenzyme M reductase operon protein C.
    
   0.649
metN2
Methionine import ATP-binding protein MetN 2.
    
   0.649
KZX10091.1
Hypothetical protein.
    
   0.649
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.