STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
metCCystathionine beta-lyase. (392 aa)    
Predicted Functional Partners:
cysK1
O-acetylserine sulfhydrylase.
 
 0.997
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
  
 
 0.946
asnB
Asparagine synthetase B.
 
 
 0.913
ahcY
Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family.
  
 0.907
mdeA
Methionine gamma-lyase.
  
 
 0.896
patA
Putative N-acetyl-LL-diaminopimelate aminotransferase.
  
 
 0.894
hom_1
Homoserine dehydrogenase.
  
 
 0.872
hom_2
Homoserine dehydrogenase.
  
 
 0.872
cysE
Serine acetyltransferase.
  
 
 0.851
coaBC
Coenzyme A biosynthesis bifunctional protein CoaBC.
   
 
  0.785
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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