Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
KZX12684.1Shwachman-bodian-diamond syndrome (SBDS) protein. (233 aa)    
Predicted Functional Partners:
rpl37ae
50S ribosomal protein L37Ae; Binds to the 23S rRNA.
  
   0.981
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
 
 0.977
rpsI
30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
  
 
 0.972
fusA
Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
 
 
 0.945
KZX10749.1
50S ribosomal protein L14e.
   
 
 0.932
rpl15e
50S ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.
 
 
 0.930
rpmD
50S ribosomal protein L30.
  
 
 0.915
eif6
Translation initiation factor IF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
 
 
 0.898
prcA
Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
   
 0.896
rpl7ae
Putative ribosomal protein L7Ae-like protein; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
   
 
 0.868
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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