Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trmItRNA (adenine(58)-N(1))-methyltransferase TrmI. (243 aa)    
Predicted Functional Partners:
tgt_1
Queuine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
  
  
 0.860
pyrB
Aspartate carbamoyltransferase.
       0.805
rlmE
Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
   
  
 0.764
dbpA_2
ATP-dependent RNA helicase DbpA.
 
     0.724
rps8e
30S ribosomal protein S8e.
 
    0.693
rpmD
50S ribosomal protein L30.
   
   0.669
obgE
GTPase ObgE/CgtA.
   
    0.638
KZX12131.1
H/ACA RNA-protein complex component Gar1.
   
  
 0.635
ttcA_1
tRNA 2-thiocytidine biosynthesis protein TtcA.
 
  
 0.600
ttcA_2
tRNA 2-thiocytidine biosynthesis protein TtcA.
 
  
 0.583
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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