Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
cbiEPutative cobalt-precorrin-6Y C(5)-methyltransferase. (211 aa)    
Predicted Functional Partners:
cobH
precorrin-8X methylmutase.
 
 
 0.999
cbiT
Putative cobalt-precorrin-6Y C(15)-methyltransferase; Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
 
 0.998
cbiD
cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
 
 0.984
KZX17605.1
Cobalamin biosynthesis protein CbiG.
 
  
 0.979
cbiL
Cobalt-precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.970
cbiF
Cobalt-precorrin-4 C(11)-methyltransferase.
 
 
 0.969
cbiH
cobalt-precorrin-3B C(17)-methyltransferase.
 
 
0.926
cobB_1
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
 
  
 0.846
bchI
Magnesium-chelatase 38 kDa subunit.
  
  
 0.748
cbiM_2
Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
  
 0.744
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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